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Glucocorticoids and treating Lymphoma in dogs and cats: Thinking twice before using them prematurely in Lymphoma

What are glucocorticoids?  Glucocorticoids are steroid hormones naturally produced by the adrenal cortex but can also be given as medications e.g. Prednisolone and dexamethasone. How do they affect lymphoma? Glucocorticoids help destroy lymphoma cells in dogs and cats primarily through inducing apoptosis— a form of programmed cell death — especially in lymphoid cells, including B and T lymphocytes. There are several mechanisms by which they destroy lymphoma cells: Binding to Glucocorticoid Receptors Glucocorticoids enter lymphoma cells and bind to cytoplasmic glucocorticoid receptors (GRs). This complex moves into the nucleus and affects gene transcription. Altered Gene Expression They upregulate pro-apoptotic genes…
Kaitlin Hattle
July 18, 2025
General

Cruz’s Journey: From Elbow Fracture to Recovery

  The handsome Cruz Cruz presented to our orthopaedic department after becoming acutely non–weight-bearing lame on his right forelimb. A CT scan of the forelimb confirmed a lateral condylar fracture, along with a non-displaced medial condylar fissure (a break on the outer part of the elbow joint—and a small crack on the inner side). Image on the left shows the fissure line through the medial epicondyle (red arrows) and the extensive epicondylar remodelling (blue arrows). Image on the right is a 3D CT reconstruction of the lateral condylar fracture. Surgical repair involved making an incision over the outer aspect of…
Kaitlin Hattle
July 11, 2025
General

The Power of Multidisciplinary Care at Bridge Referrals

At Bridge Referrals, collaboration is at the heart of everything we do. By bringing together experts from different disciplines, we’re able to offer truly comprehensive care — especially in complex cases that require more than one area of expertise. In this blog, we’re sharing the journey of Jasper, a much-loved patient who recently benefited from our unique multidisciplinary approach. With the combined knowledge and skill of our ophthalmology, oncology, and soft tissue surgery teams, Jasper received a tailored treatment plan that not only targeted a serious condition but also gave him the best chance of keeping his eye — and…
Kaitlin Hattle
June 24, 2025
General

Janette Bailey Woods joins the Bridge Referrals Team as Lead Anaesthesia Nurse

Janette recently joined the Bridge Referrals team as our lead anaesthesia nurse. She brings with her a wealth of experience and will be working to ensure that our patients receive the most up-to-date care during their anaesthesia, as well as providing advanced pain relief techniques. Janette Bailey Woods RVN, NCert (Anaesthesia & ECC), VTS (Anaesthesia & Analgesia) Janette qualified as a RVN (Registered Veterinary Nurse) in 2001 and initially worked in mixed animal practice in Cumbria for 15 years. Between 2013 and 2025 she worked in two large referral hospitals, during which time she gained a certificate in Emergency &…
Kaitlin Hattle
May 23, 2025
General

Waffle’s Patent Ductus Arteriosus journey at Bridge Referrals

We've created a short video of Waffle, the Cocker Spaniels, PDA treatment at Bridge Referrals. Karl Bovenizer, our Cardiologist, created this case study for you. We've generated this video using Google's AI engine. (Google has given Karl an American accent however he is a very proud Dubliner.) To refer to our Cardiology Team use our platform or email us: Click - Referral Platform  Email - [email protected]    
Kaitlin Hattle
March 31, 2025